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Metaculus is an online forecasting platform focusing on topics of global importance.

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When will Altos Labs first trial an anti-aging intervention in humans?

09 Aug 2030 (29 Jul 2028 - Aug 2033)

12
33 comments
20
20 forecasters
09 Aug 2030
(29 Jul 2028 - Aug 2033)

Will there be an FDA-approved cure for Type 1 diabetes before January 1, 2032?

15% chance

2
88 comments
21
21 forecasters
15%chance

Will the US, UK or EU approve a gene editing therapy for a new condition during 2026?

9% chance

1
2121 comments
765
765 forecasters
9%chance

What will be the lower 95% confidence bound for the vaccine efficacy of the M72 tuberculosis vaccine in the Phase 3 Gates MRI trial?

18.8% (7.13 - 30.6)

1
2424 comments
19
19 forecasters
18.8%
(7.13 - 30.6)

What vaccine efficacy will the MTBVAC tuberculosis vaccine show in the IMAGINE phase 2 clinical trial?

35.4% (21.3 - 50.9)

2
2121 comments
19
19 forecasters
35.4%
(21.3 - 50.9)

What will be the lower confidence bound for the vaccine efficacy of the MTBVAC tuberculosis vaccine in the IMAGINE Phase 2 clinical trial?

0.89% (<0 - 13.5)

2020 comments
18
18 forecasters
0.89%
(<0 - 13.5)

What vaccine efficacy will the M72 tuberculosis vaccine show in the Phase 3 Gates MRI trial?

45.7% (34.9 - 55.6)

1
1818 comments
20
20 forecasters
45.7%
(34.9 - 55.6)

Will a senolytic therapy be approved for commercial sale by the US FDA before January 1, 2030?

33% chance

42
3636 comments
156
156 forecasters
33%chance

Will an inorganic nanoparticle-enabled cancer therapy be approved by the FDA before 2031?

49% chance

7
22 comments
34
34 forecasters
49%chance

Will an inorganic nanoparticle-enabled cancer therapy be approved by the FDA before 2041?

80% chance

8
0 comments
29
29 forecasters
80%chance

How many cluster-randomized trials will be published before 2027 assessing whether far-UVC reduces transmission of airborne pathogens?

1.42 CRT (0.748 - 2.59)

1
55 comments
5
5 forecasters
1.42 CRT
(0.748 - 2.59)

When will pig-to-human xenotransplantation become a routine medical procedure?

Apr 2042 (Jan 2035 - Oct 2047)

6
33 comments
14
14 forecasters
Apr 2042
(Jan 2035 - Oct 2047)

Efficacy confirmation of a new Alzheimer's treatment protocol?

result: no

14
66 comments
118
118 forecasters
ResolvedNo

Will a universal allogeneic cell therapy platform receive FDA approval before 2035?

50% chance

2
11 comment
8
8 forecasters
50%chance

Allogeneic cell therapy FDA approved by 2035? โ†’ Will cancer mortality โ†“ by 50% by 2051?

1
0 comments
9
9 forecasters

When will the first medical treatment based on nanorobots happen?

Oct 2031 (27 Jan 2029 - Jun 2035)

9
88 comments
13
13 forecasters
Oct 2031
(27 Jan 2029 - Jun 2035)

Will the cancer pill AOH1996 enter Phase III clinical trials before January 1, 2027?

8% chance

5
22 comments
15
15 forecasters
8%chance

Will any of the ongoing BioNTech mRNA cancer vaccine trials proceed to Phase III trials in 2022?

result: no

8
1111 comments
61
61 forecasters
ResolvedNo

Will a biologic therapy targeting Mycobacterium tuberculosis be tested in humans before 2038?

53% chance

3
44 comments
20
20 forecasters
53%chance

Will stage-3 trials of MDMA as a medical treatment be completed, with results submitted to the FDA, by 2021?

result: no

21
88 comments
149
149 forecasters
ResolvedNo

Clinical trial of new treatment for sepsis?

result: yes

4
99 comments
50
50 forecasters
ResolvedYes

At last? Clinical trials of a vaccine for the common cold?

result: no

11
44 comments
50
50 forecasters
ResolvedNo